Why does only one knee hurt? ScanAlign private EOS imaging clinic, Harley Street, London
Knee alignment

Why Does Only One Knee Hurt? Understanding Knee Pain on One Side

Pain in only one knee is rarely just about that knee. A difference in leg length, a tilted pelvis, or years of favouring one side can put extra load on a single joint. Standing whole-body imaging lets you compare both legs side by side. It shows whether an alignment problem somewhere else is making one knee work harder than the other.

Key takeaways

  • Knee pain on one side often points to a whole-body alignment problem, not just a local injury.
  • A leg length discrepancy of just a few millimetres can overload one knee over time.
  • Lying-down scans relax your muscles and can hide the imbalance that appears when you stand.
  • EOS standing imaging captures both legs on a single image, so your clinician can compare them directly.
  • If you have sudden swelling, locking, giving way, or cannot bear weight, see your doctor or go to the emergency department first.

You use both knees equally, or so it feels. Yet one aches after a walk, stiffens on the stairs, or swells by the end of the day. The other feels completely fine. That difference is a clue worth following.

Most scans of a single area look only at the painful knee. That is useful for spotting cartilage damage or arthritis in that joint. But it cannot answer a bigger question: why is this knee wearing out faster than the other one?


What does knee pain on one side feel like?

It can show up in many ways, and the pattern often changes with activity. Here are some of the most common signs people describe.

Aching after walking

A dull ache that builds in one knee during or after a walk, while the other side stays comfortable.

Stiffness on stairs

One knee feels tight or catches when going up or down stairs, especially first thing in the morning.

Swelling on one side

The affected knee puffs up by the evening or after exercise, while the other looks normal.

Pain on the inner or outer side

Pain focused on the inside or outside of one knee, often linked to how load travels through that leg.

Important. If your knee is hot, very swollen, locked in position, or you cannot put any weight on it, please see your doctor, call your local emergency number, or go to the emergency department. These signs need urgent assessment, not a scan booking.


What causes pain in one knee only?

Several things can overload a single knee. Some are in the joint itself. Others start higher up or lower down the body. They only show themselves when you look at the whole picture.

Leg length difference

Even a small difference means one knee takes more force with every step. Over the years, the wear adds up.

Pelvic tilt

A lateral pelvic tilt shifts your centre of gravity sideways and sends extra load through one leg.

Knee alignment (valgus or varus)

If one knee angles inward or outward more than the other, load builds up on one compartment of the joint.

Overuse of the dominant leg

You naturally push off harder with your dominant leg. Over time, that joint builds up more stress.

Past injuries matter too. An old ankle sprain, a hip problem, or even the way you usually stand can quietly change how force passes through one leg. You can read more in can poor posture cause hip, knee and back pain.


How does a problem elsewhere end up in your knee?

Your body works as a connected chain, from your feet up through your hips and spine. When one link shifts, the links above and below make up for it. That compensation is often invisible. It does not hurt where it starts. It hurts where it finishes.

Why does only one knee hurt? ScanAlign clinic illustration

For example, a small leg length discrepancy tilts the pelvis. That tilt changes the angle at the hip. The hip angle changes how weight passes through the knee below. The knee on the longer leg, or on the side that compensates most, ends up doing more work. Year after year, that extra load adds up.

This is why scanning only the painful knee can miss the real cause. The knee itself may look fairly normal. Yet the reason it hurts lies in how the whole chain is aligned while you stand.


How does a standing scan help with knee pain on one side?

A standing scan captures your skeleton while it carries your real body weight, the same conditions in which your pain actually happens. Lying-down imaging relaxes your muscles and lets your joints settle into a neutral position. That can hide the very imbalance causing your problem.

You stand naturally while the EOS system captures a full image from your hips to your ankles, or from head to foot, in a single pass. Both legs appear on the same image at the same scale. Your clinician can compare the alignment of your left and right sides directly. They can measure any imbalance that appears only when you are bearing weight.

EOS uses about 90% less radiation than a standard X-ray, around ten times less. A full-leg standing x-ray like this gives a clear picture of how your joints line up in real life.

A standard X-ray or MRI is taken while you lie on a table. Gravity is removed, muscles relax, and the joints settle differently than when you stand. The image shows only the area requested, often just one knee. There is no easy way to compare the two legs side by side, or to see whether a tilt higher up is shifting load downward.

At ScanAlign, whole-body standing imaging, both legs are captured in a single exposure. That means one image, one moment, no stitching and no magnification errors. It is the clearest way to see whether something above or below the knee is driving the problem in that joint.

When MRI is the better choice. EOS shows bones, joints and alignment beautifully. But if your clinician suspects a torn meniscus, ligament damage, or a problem with soft tissue, discs or nerves, MRI is usually the better tool. The two scans answer different questions and often work well together.


What can you do about knee pain on one side?

The most useful first step is understanding what is happening. Without knowing whether the problem is in the knee itself or driven by alignment higher up, it is hard for any professional to choose the right approach. Here is what usually helps people move forward.

  • Get a clear picture. A standing whole-body image lets your clinician see both legs, your pelvis and your spine in one view. That context matters.
  • Share it with your team. Whether you see a physiotherapist, osteopath or orthopaedic surgeon, the image gives them objective information to plan around.
  • Address the cause, not just the symptom. If a pelvic tilt or leg length difference is overloading one knee, targeted rehabilitation or orthotics may help reduce the load on that side over time.

Before you start treatment, or change the one you are on, it is worth getting a detailed diagnosis. Knowing whether the cause sits in the pelvis, the legs or the spine changes what will actually help.

Wondering whether your knee pain could be an alignment problem? A free video consultation can help you decide if a standing scan in London is the right next step.

Book a free video consultation

Frequently asked questions about knee pain on one side

Knee pain on one side usually means one knee is under more mechanical stress than the other. Common reasons include a difference in leg length, a tilted pelvis, a past injury on one side, or natural dominance of one leg. A whole-body standing image can reveal these differences.

Yes. Even a small difference shifts extra load onto one side with every step. Over months and years, that added stress can speed up wear in the cartilage and joint surfaces of the overloaded knee.

Not in terms of what causes it. Whether the left or right knee hurts depends on which side is taking more load. The underlying causes, such as alignment, leg length and the position of the pelvis, are the same on either side.

Walking puts your joints under load. An alignment problem that is invisible at rest becomes clear when gravity and the forces from the ground are involved. This is exactly why standing imaging can show problems that lying-down scans miss.

No. ScanAlign accepts self-referrals. You can book a full-body standing scan directly, starting with a free video consultation to make sure the scan is right for you.

EOS uses about 90% less radiation than a standard X-ray, around ten times less. It is one of the lowest-dose skeletal imaging systems available.

The price for patients travelling from abroad is confirmed during the free video consultation.

EOS is designed for bones, joints and alignment. For soft tissues such as cartilage, ligaments and menisci, MRI is usually the better tool. Your clinician may recommend both types of imaging if needed.

You stand still inside the EOS scanner while it takes a full-length image. The scan itself takes only a few seconds. You stay clothed and there is no enclosed tunnel.

Absolutely. Your images and report are yours. Many people share them with their physiotherapist, osteopath or orthopaedic consultant to guide the next steps in their care.

Find out why one knee is doing all the work

A free video consultation helps you understand whether a standing whole-body scan at 19 Harley Street, London could reveal the cause of your knee pain on one side.

Book a free video consultation

Sources

  1. Illés, T. and Somoskeöy, S. (2012). The EOS imaging system and its uses in daily orthopaedic practice. International Orthopaedics, 36(7), pp. 1405-1411.
  2. NHS (2023). Knee pain. nhs.uk. Available at: https://www.nhs.uk/conditions/knee-pain/
  3. Sabharwal, S. and Kumar, A. (2008). Methods for assessing leg length discrepancy. Clinical Orthopaedics and Related Research, 466(12), pp. 2910-2922.

Written by Abbas Dhami (Specialist Diagnostic Radiographer)

This page is general information and not a diagnosis.

ScanAlign is the trading name of CoreMed Solutions Ltd and operates under The Harley Street Hospital's CQC licence.